Lane Lab

Ovarian Cancer Projects

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New and Ongoing projects:

BRCA1 Studies:

Comparative analysis of BRCT Functions

In vivo analysis of BRCA1 and BRCA1 Interacting Proteins in Mice

Transgenic mouse models of BRCA1 loss-of-function and gene replacement therapy

Functional Screening for tumor suppressor genes in mammalian cells:

cDNA screens for activators of tumor suppressor pathways in Breast Cell Lines

High throughput genetic screens for novel tumor suppressor genes.


Angiogenesis in Tumors Project:

cDNA screens for genes invoved in tumor angiogenesis repair

Analysis of gene expression in tumors arrising in transgenic mice.

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