Lane Laboratory


Papers and Manuscripts


Recent Publications

  • Chadwick BP, Lane TF. BRCA1 associates with the inactive X chromosome in late S-phase, coupled with transient H2AX phosphorylation. Chromosoma. 2005 Dec;114(6):432-9. [PDF]

  • Narko K, Zweifel B, Trifan O, Ristimaki A, Lane TF, Hla T. COX-2 inhibitors and genetic background reduce mammary tumorigenesis in cyclooxygenase-2 transgenic mice. Prostaglandins Other Lipid Mediat. 2005 May;76(1-4):86-94. [PDF]

  • Chang SH, Ai Y, Breyer RM, Lane TF, Hla T. The prostaglandin E2 receptor EP2 is required for cyclooxygenase 2-mediated mammary hyperplasia. Cancer Res. 2005 Jun 1;65(11):4496-9. [PDF]

  • Bennett CN, Longo KA, Wright WS, Suva LJ, Lane TF, Hankenson KD, MacDougald OA.
    Regulation of osteoblastogenesis and bone mass by Wnt10b. Proc Natl Acad Sci U S A. 2005 Mar 1;102(9):3324-9. [PDF]

  • Lane TF. BRCA1 and transcription. Cancer Biol Ther. 2004 Jun;3(6):528-33. [PDF]

  • Chang SH, Liu CH, Conway R, Han DK, Nithipatikom K, Trifan OC, Lane TF, Hla T.
    Role of prostaglandin E2-dependent angiogenic switch in cyclooxygenase 2-induced breast cancer progression. Proc Natl Acad Sci U S A. 2004 Jan 13;101(2):591-6. [PDF]

  • Krum SA, Miranda GA, Lin C, Lane TF. BRCA1 associates with processive RNA polymerase II. J Biol Chem. 2003 Dec 26;278(52):52012-20. [PDF]

  • Krum SA, Womack JE, Lane TF. Bovine BRCA1 shows classic responses to genotoxic stress but low in vitro transcriptional activation activity. Oncogene. 2003 Sep 4;22(38):6032-44. [PDF]

  • Liu CH, Chang SH, Narko K, Trifan OC, Wu MT, Smith E, Haudenschild C, Lane TF, Hla T (2001) Overexpression of cyclooxygenase-2 is sufficient to induce tumorigenesis in transgenic mice. J Biol Chem. 276(21):18563-9. [PDF]

  • Lane TF, Lin C, Brown MA, Solomon E, Leder P. (2000) Gene replacement with the human BRCA1 locus: tissue specific expression and rescue of embryonic lethality in mice. Oncogene 19: 4085-4090. [PDF]

  • Pepper MS, Baetens D, Mandriota S, DiSanza C, Oikemus S, Lane TF, Soriano J, Montesano R, Iruela-Arispe ML (2000) Regulation of VEGF and VEGF receptor expression in the rodent mammary gland during pregnancy, lactation, and involution. Dev. Dyn. 218: 507-524. [PDF]

  • Lane TF, Leder P (1997) Wnt-10b directs hypermorphic development and transformation in mammary glands of male and female mice. Oncogene 15: 2133-2144. [PDF]

  • Vazquez F, Hastings G, Ortega MA, Lane TF, Oikemus S, Lombardo M, Iruela-Arispe ML (1999) METH1, a human orthologue of ADAMTS and METH2 are members of a new family of proteins with angio-inhibitory activity. J. Biol. Chem. 274: 23349-23357. [PDF]


  • Lane TF, Deng C, Elson A., Kozak C, Leder, P (1995) Expression of Brca1 is associated with terminal differ-entiation of ectodermally and mesodermally derived tissues in mice. Genes and Development 9: 2712-2722. [PDF]


    Book Chapters

    • Lane TF, Collado-Hidalgo A (2001). Oncogenes, anti-oncogenes, and genetic regulators of vascular development. Chapter in Vascular Morphogenesis in the Female Reproductive System. Eds Augustin HG, Iruela-Arispe L, Rogers P, Smith S Springer-Birkhaeuser, New York. [Publisher Site] [PDF]



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