We are a computational biology lab within the Department of Biological Chemistry in the David Geffen School of Medicine and also part of the Computer Science Department, the Interdepartmental Bioinformatics Program, the Institute for Quantitative and Computational Biosciences, the Broad Stem Cell Research Center, the Jonsson Comprehensive Cancer Center, and the Molecular Biology Institute at UCLA.

The focus of the lab is on developing and applying machine learning methods for the analysis of high-throughput experimental data to address problems in epigenomics and gene regulation. Our research is often conducted in close collaboration with experimental groups. Please see the publications page to learn more about the lab's research.

We are recruiting new members, if interested please see the positions page.

Recent News

  • February 2015: Jason's work on large-scale epigenomic imputation is now published online at the journal Nature Biotechnology and the associated ChromImpute software is publicly released.
  • February 2015: The Roadmap Epigenomics Consortium publishes the Integrative analysis of 111 reference human epigenomes in the journal Nature. Jason is one of the co-first authors on the paper. The Roadmap Epigenomics project receives extensive media coverage (e.g. NY Times, Washington Post).

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    Upcoming Presentations

  • March 9: International Conference on Bioinformatics and Computational Biology (keynote talk)
  • March 30: Keystone Epigenomics Meeting - Roadmap Epigenomics Tutorial