Shivan Bonanno

Shivan Bonanno


Undergraduate: UC Berkeley, Molecular Cellular Biology - Neurobiology

Research interest: 

Long-lasting changes in synaptic connectivity in the brain, such as those that underlie memory formation, require changes in gene expression. My research addresses the transport of signals from the synapse to the nucleus following induction of long-term neuronal plasticity. I focus on the synapse to nuclear transport of the transcriptional regulator CRTC1. My research tests the hypothesis that activity-dependent changes in the post-translational modification of CRTC1 encode distinct patterns of synaptic activity and couple them to specific programs of gene expression.



2015-2017 NSRA Award