Tamir Gonen

Office: 

377B BSRB
615 Charles Young Dr.
David Geffen School of Medicine at UCLA
Department of Biological Chemistry
Los Angeles, CA 90095
 

Lab: 

611 Charles E. Young Dr. East
539 Boyer Hall UCLA
Los Angeles CA 90095
 

Tamir Gonen

Position Titles: 

2002 - 2005      Postdoctoral fellow, Harvard Medical School

2005 - 2010      Assistant Professor, University of Washington School of Medicine

2009 - 2011      Early Career Scientist, Howard Hughes Medical Institute

2010 - 2011      Associate Professor with Tenure, University of Washington School of Medicine

2011 – 2017    Group Leader, Janelia Research Campus, Howard Hughes Medical Institute

2017 – Current, Professor, Biological Chemistry and Physiology, David Geffen School Of Medicine, University of California, Los Angeles

2017 – Current Investigator, Howard hughes Medical Institute

Biography: 

 Dr Gonen is an expert in electron crystallography and cryo EM. He determined the 1.9Å resolution structure of the water channel aquaporin-0 by electron crystallography, the highest resolution for any protein determined by cryo EM techniques at the time. Dr Gonen established his own laboratory at the University of Washington in 2005 together with the very first cryo EM laboratory in the Pacific Northwest, a resource that continues to benefit many researchers at the UW School of Medicine and beyond. He has authored many publications from his laboratory concerning membrane protein structure and function. Dr Gonen was honored with a Career Development award from the American Diabetes Association as well as being chosen one of only 50 Howard Hughes Medical Institute Early Career Scientists around the country. In 2011 Dr Gonen accepted a position as a Group Leader at the HHMI Janelia Research Campus where he began developing MicroED as a new method for structural biology. With this method Dr Gonen has pushed the boundaries of cryoEM and determined a number of previously unknown structures at resolutions close to 1Å. In 2012 he became a Member of the Royal Society of New Zealand and in a Professor of Biological Chemistry and Physiology at the David Geffen School of Medicine of the University of California, Los Angeles and an Investigator of the Howard Hughes Medical Institute.

 

Research interest: 

 

Our laboratory studies the structures of membrane proteins important in homeostasis and signaling. We develop new tools in structural biology, namely MicroED as a new method for cryo EM, to facilitate the study of such membrane proteins to atomic resolution from vanishingly small crystals.

 

Awards/Honors: 

1996                 Deans List - Organic Chemistry, University of Auckland, New Zealand

1996                 Deans List - Inorganic Chemistry, University of Auckland, New Zealand

1997                 Center for Gene Technology Research Scholarship, University of Auckland, New Zealand

1997                 Deans List - Inorganic Chemistry, University of Auckland, New Zealand

1998                 Senior Prize in Biological Sciences, University of Auckland, New Zealand

1998                 First Class Honors in Biological Sciences, University of Auckland, New Zealand

1999                 University of Auckland Doctoral Scholarship, University of Auckland, New Zealand

2000                 Contestable Travel Fund Award, University of Auckland, New Zealand

2001                 Contestable Travel Fund Award, University of Auckland, New Zealand

2009                 American Diabetes Association Career Development Award

2009                 Howard Hughes Medical Institute Early Career Scientist

2010                 New Investigator Science in Medicine Lecture

2012                 Member, The Royal Society of New Zealand

2017                Investigator, Howard Hughes Medical Institute